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1

Effect of Surface Coating with Magnesium StearateviaMechanical Dry Powder Coating Approach on the Aerosol Performance of Micronized Drug Powders from Dry Powder Inhalers

Qi (Tony) Zhou, Li Qu, Thomas Gengenbach, Ian Larson, Peter J. Stewart…

Journal:

AAPS PharmSciTech

Année:

2013

Langue:

english

Fichier:

PDF, 239 KB

english, 2013

2

Dry powder inhaler formulations of poorly water-soluble itraconazole: A balance between in-vitro dissolution and in-vivo distribution is necessary

Huang, Zhengwei, Lin, Ling, McGoverin, Cushla, Liu, Hu, Wang, Lili, Zhou, Qi (Tony), Lu, Ming, Wu, Chuanbin

Journal:

International Journal of Pharmaceutics

Année:

2018

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2018

3

Improving aerosolization of drug powders by reducing powder intrinsic cohesion via a mechanical dry coating approach

Qi Tony Zhou, Li Qu, Ian Larson, Peter J. Stewart, David A.V. Morton

Journal:

International Journal of Pharmaceutics

Année:

2010

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2010

4

Inhaled formulations and pulmonary drug delivery systems for respiratory infections

Zhou, Qi (Tony), Leung, Sharon Shui Yee, Tang, Patricia, Parumasivam, Thaigarajan, Loh, Zhi Hui, Chan, Hak-Kim

Journal:

Advanced Drug Delivery Reviews

Année:

2015

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2015

5

Understanding the Impacts of Surface Compositions on the In-Vitro Dissolution and Aerosolization of Co-Spray-Dried Composite Powder Formulations for Inhalation

Mangal, Sharad, Xu, Rongkun, Park, Heejun, Zemlyanov, Dmitry, Shetty, Nivedita, Lin, Yu-Wei, Morton, David, Chan, Hak-Kim, Li, Jian, Zhou, Qi Tony

Journal:

Pharmaceutical Research

Année:

2019

Langue:

english

Fichier:

PDF, 3.11 MB

english, 2019

6

Inhaled anti-infective chemotherapy for respiratory tract infections: Successes, challenges and the road ahead

Velkov, Tony, Abdul Rahim, Nusaibah, Zhou, Qi (Tony), Chan, Hak-Kim, Li, Jian

Journal:

Advanced Drug Delivery Reviews

Année:

2015

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2015

7

Novel Inhaled Combination Powder Containing Amorphous Colistin and Crystalline Rifapentine with Enhanced Antimicrobial Activities against Planktonic Cells and Biofilm of Pseudomonas aeruginosa for Respiratory Infections

Zhou, Qi (Tony), Sun, Si-Ping, Chan, John Gar Yan, Wang, Ping, Barraud, Nicolas, Rice, Scott A., Wang, Jiping, Li, Jian, Chan, Hak-Kim

Journal:

Molecular Pharmaceutics

Année:

2014

Langue:

english

Fichier:

PDF, 8.47 MB

english, 2014

8

Investigation of the potential for direct compaction of a fine ibuprofen powder dry-coated with magnesium stearate

Qu, Li, Zhou, Qi (Tony), Gengenbach, Thomas, Denman, John A., Stewart, Peter J., Hapgood, Karen P., Gamlen, Michael, Morton, David A. V.

Journal:

Drug Development and Industrial Pharmacy

Année:

2015

Langue:

english

Fichier:

PDF, 987 KB

english, 2015

9

Stability of pharmaceutical salts in solid oral dosage forms

Nie, Haichen, Byrn, Stephen R., Zhou, Qi (Tony)

Journal:

Drug Development and Industrial Pharmacy

Année:

2017

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2017

10

Influence of excipients on physical and aerosolization stability of spray dried high-dose powder formulations for inhalation

Shetty, Nivedita, Park, Heejun, Zemlyanov, Dmitry, Mangal, Sharad, Bhujbal, Sonal, (Tony) Zhou, Qi

Journal:

International Journal of Pharmaceutics

Année:

2018

Langue:

english

Fichier:

PDF, 3.05 MB

english, 2018

11

Composite particle formulations of colistin and meropenem with improved in-vitro bacterial killing and aerosolization for inhalation

Mangal, Sharad, Park, Heejun, Zeng, Lingfei, Yu, Heidi H., Lin, Yu-wei, Velkov, Tony, Denman, John A., Zemlyanov, Dmitry, Li, Jian, Zhou, Qi Tony

Journal:

International Journal of Pharmaceutics

Année:

2018

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2018

12

Simultaneous Particle Size Reduction and Homogeneous Mixing to Produce Combinational Powder Formulations for Inhalation by the Single-Step Co-Jet Milling

Ling, Junhong, Mangal, Sharad, Park, Heejun, Wang, Shaoning, Cavallaro, Alex, Zhou, Qi Tony

Journal:

Journal of Pharmaceutical Sciences

Année:

2019

Fichier:

PDF, 1.25 MB

2019

13

Physical stability of dry powder inhaler formulations

Shetty, Nivedita, Cipolla, David, Park, Heejun, Zhou, Qi Tony

Journal:

Expert Opinion on Drug Delivery

Année:

2019

Fichier:

PDF, 2.18 MB

2019

14

Characterization of the surface properties of a model pharmaceutical fine powder modified with a pharmaceutical lubricant to improve flow via a mechanical dry coating approach

Qi (Tony) Zhou, John A. Denman, Thomas Gengenbach, Shyamal Das, Li Qu, Hailong Zhang, Ian Larson, Peter J. Stewart, David A. V. Morton

Journal:

Journal of Pharmaceutical Sciences

Année:

2011

Langue:

english

Fichier:

PDF, 383 KB

english, 2011

15

Investigation of the extent of surface coating via mechanofusion with varying additive levels and the influences on bulk powder flow properties

Qi (Tony) Zhou, Li Qu, Thomas Gengenbach, John A. Denman, Ian Larson, Peter J. Stewart, David A.V. Morton

Journal:

International Journal of Pharmaceutics

Année:

2011

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2011

16

Effect of mechanical dry particle coating on the improvement of powder flowability for lactose monohydrate: A model cohesive pharmaceutical powder

Qi (Tony) Zhou, Li Qu, Ian Larson, Peter J. Stewart, David A.V. Morton

Journal:

Powder Technology

Année:

2011

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2011

17

Drug–lactose binding aspects in adhesive mixtures: Controlling performance in dry powder inhaler formulations by altering lactose carrier surfaces

Qi (Tony) Zhou, David A.V. Morton

Journal:

Advanced Drug Delivery Reviews

Année:

2012

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2012

18

Understanding the influence of powder flowability, fluidization and de-agglomeration characteristics on the aerosolization of pharmaceutical model powders

Qi Tony Zhou, Brian Armstrong, Ian Larson, Peter J. Stewart, David A.V. Morton

Journal:

European Journal of Pharmaceutical Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2010

19

Effect of Device Design on the Aerosolization of a Carrier-Based Dry Powder Inhaler—a Case Study on Aerolizer®Foradile®

Zhou, Qi Tony, Tong, Zhenbo, Tang, Patricia, Citterio, Mauro, Yang, Runyu, Chan, Hak-Kim

Journal:

The AAPS Journal

Année:

2013

Langue:

english

Fichier:

PDF, 855 KB

english, 2013

20

Emerging inhalation aerosol devices and strategies: Where are we headed?

Zhou, Qi (Tony), Tang, Patricia, Leung, Sharon Shui Yee, Chan, John Gar Yan, Chan, Hak-Kim

Journal:

Advanced Drug Delivery Reviews

Année:

2014

Langue:

english

Fichier:

PDF, 1.25 MB

english, 2014

21

Advances in Device and Formulation Technologies for Pulmonary Drug Delivery

Chan, John Gar Yan, Wong, Jennifer, Zhou, Qi Tony, Leung, Sharon Shui Yee, Chan, Hak-Kim

Journal:

AAPS PharmSciTech

Année:

2014

Langue:

english

Fichier:

PDF, 459 KB

english, 2014

22

Relationship between processing, surface energy and bulk properties of ultrafine silk particles

Rajkhowa, Rangam, Kafi, Abdullah, Zhou, Qi Tony, Kondor, Anett, Morton, David A.V., Wang, Xungai

Journal:

Powder Technology

Année:

2015

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2015

23

Colistin Powders with High Aerosolisation Efficiency for Respiratory Infection: Preparation and In Vitro Evaluation

Zhou, Qi Tony, Morton, David A. V., Yu, Heidi H., Jacob, Jovan, Wang, Jiping, Li, Jian, Chan, Hak Kim

Journal:

Journal of Pharmaceutical Sciences

Année:

2013

Langue:

english

Fichier:

PDF, 4.74 MB

english, 2013

24

Inhalable Dry Powder Formulations of siRNA and pH-Responsive Peptides with Antiviral Activity Against H1N1 Influenza Virus

Liang, Wanling, Chow, Michael Y. T., Lau, Pui Ngan, Zhou, Qi Tony, Kwok, Philip C. L., Leung, George P. H., Mason, A. James, Chan, Hak-Kim, Poon, Leo L. M., Lam, Jenny K. W.

Journal:

Molecular Pharmaceutics

Année:

2015

Langue:

english

Fichier:

PDF, 5.94 MB

english, 2015

25

Isolation and Characterization of Cancer Stem Cells from High-Grade Serous Ovarian Carcinomas

He, Qi-zhi, Luo, Xun-zhen, Wang, Kai, Zhou, Qian, Ao, Hong, Yang, Yan, Li, Shu-xia, Li, Ying, Zhu, Hui-ting, Duan, Tony

Journal:

Cellular Physiology and Biochemistry

Année:

2014

Langue:

english

Fichier:

PDF, 2.06 MB

english, 2014

26

Influence of coating material on the flowability and dissolution of dry-coated fine ibuprofen powders

Qu, Li, Zhou, Qi (Tony), Denman, John A., Stewart, Peter J., Hapgood, Karen P., Morton, David A.V.

Journal:

European Journal of Pharmaceutical Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 1.46 MB

english, 2015

27

Investigation of the Changes in Aerosolization Behavior Between the Jet-Milled and Spray-Dried Colistin Powders Through Surface Energy Characterization

Jong, Teresa, Li, Jian, Morton, David A.V., Zhou, Qi (Tony), Larson, Ian

Journal:

Journal of Pharmaceutical Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2016

28

Pulmonary Delivery of the Kv1.3-Blocking Peptide HsTX1[R14A] for the Treatment of Autoimmune Diseases

Jin, Liang, Zhou, Qi (Tony), Chan, Hak-Kim, Larson, Ian C., Pennington, Michael W., Morales, Rodrigo A.V., Boyd, Ben J., Norton, Raymond S., Nicolazzo, Joseph A.

Journal:

Journal of Pharmaceutical Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 587 KB

english, 2016

29

Effects of Surface Composition on the Aerosolisation and Dissolution of Inhaled Antibiotic Combination Powders Consisting of Colistin and Rifampicin

Wang, Wenbo, Zhou, Qi Tony, Sun, Si-Ping, Denman, John A., Gengenbach, Thomas R., Barraud, Nicolas, Rice, Scott A., Li, Jian, Yang, Mingshi, Chan, Hak-Kim

Journal:

The AAPS Journal

Année:

2016

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2016

30

An “Unlikely” Pair: The Antimicrobial Synergy of Polymyxin B in Combination with the Cystic Fibrosis Transmembrane Conductance Regulator Drugs KALYDECO and ORKAMBI

Schneider, Elena K., Azad, Mohammad A. K., Han, Mei-Ling, (Tony) Zhou, Qi, Wang, Jiping, Huang, Johnny X., Cooper, Matthew A., Doi, Yohei, Baker, Mark A., Bergen, Phillip J., Muller, Mark T., Li, Jian

Journal:

ACS Infectious Diseases

Année:

2016

Langue:

english

Fichier:

PDF, 4.53 MB

english, 2016

31

Pharmacokinetics/Pharmacodynamics of Pulmonary Delivery of Colistin against Pseudomonas aeruginosa in a Mouse Lung Infection Model

Lin, Yu-Wei, Zhou, Qi Tony, Cheah, Soon-Ee, Zhao, Jinxin, Chen, Ke, Wang, Jiping, Chan, Hak-Kim, Li, Jian

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2017

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2017

32

AIP Conference Proceedings [AIP POWDERS AND GRAINS 2013: Proceedings of the 7th International Conference on Micromechanics of Granular Media - Sydney, Australia (8–12 July 2013)] - CFD analysis of the aerosolization of carrier-based dry powder inhaler formulations

Zhou, Qi (Tony), Tong, Zhenbo, Tang, Patricia, Yang, Runyu, Chan, Hak-Kim

Année:

2013

Langue:

english

Fichier:

PDF, 398 KB

english, 2013

33

Potential toxicity of polymyxins in human lung epithelial cells

Ahmed, Maizbha U., Velkov, Tony, Lin, Yu-Wei, Yun, Bo, Nowell, Cameron J., Zhou, Fanfan, Zhou, Qi Tony, Chan, Kim, Azad, Mohammad A. K., Li, Jian

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2017

Langue:

english

Fichier:

PDF, 3.59 MB

english, 2017

34

Effects of coating materials and processing conditions on flow enhancement of cohesive acetaminophen powders by high-shear processing with pharmaceutical lubricants

Wei, Guoguang, Mangal, Sharad, Denman, John, Gengenbach, Thomas, Lee Bonar, Kevin, Khan, Rubayat Islam, Qu, Li, Li, Tonglei, Zhou, Qi (Tony)

Journal:

Journal of Pharmaceutical Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2017

35

Aerosolized Polymyxin B for Treatment of Respiratory Tract Infections: Determination of Pharmacokinetic/Pharmacodynamic Indices for Aerosolized Polymyxin B against Pseudomonas aeruginosa in a Mouse Lung Infection Model

Lin, Yu-Wei, Zhou, Qi (Tony), Onufrak, Nikolas J, Wirth, Veronika, Chen, Ke, Wang, Jiping, Forrest, Alan, Chan, Hak-Kim, Li, Jian

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2017

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2017

36

Investigation of L-leucine in reducing the moisture-induced deterioration of spray-dried salbutamol sulfate power for inhalation

Li, Liang, Leung, Sharon Shui Yee, Gengenbach, Thomas, Yu, Jiaqi, Gao, Ge (Fiona), Tang, Patricia, Zhou, Qi (Tony), Chan, Hak-Kim

Journal:

International Journal of Pharmaceutics

Année:

2017

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2017

37

Pulmonary Pharmacokinetics of Colistin Following Administration of Dry Powder Aerosols in Rats

Lin, Yu-Wei, Zhou, Qi (Tony), Hu, Yang, Onufrak, Nikolas J, Sun, Siping, Wang, Jiping, Forrest, Alan, Chan, Hak-Kim, Li, Jian

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2017

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2017

38

Elucidating the Pharmacokinetics/Pharmacodynamics of Aerosolized Colistin against Multidrug-resistant Acinetobacter baumannii and Klebsiella pneumoniae in a Mouse Lung Infection Model

Lin, Yu-Wei, Zhou, Qi Tony, Han, Mei-Ling, Chen, Ke, Onufrak, Nikolas J., Wang, Jiping, Turnidge, John D., Howden, Benjamin P., Forrest, Alan, Chan, Hak-Kim, Li, Jian

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2017

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2017

39

Mechanism-based Pharmacokinetic/Pharmacodynamic Modeling of Aerosolized Colistin in a Mouse Lung Infection Model

Lin, Yu-Wei, Zhou, Qi Tony, Han, Mei-Ling, Onufrak, Nikolas J, Chen, Ke, Wang, Jiping, Forrest, Alan, Chan, Hak-Kim, Li, Jian

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2017

Langue:

english

Fichier:

PDF, 3.14 MB

english, 2017

40

Effects of Drying Process on an IgG1 Monoclonal Antibody Using Solid-State Hydrogen Deuterium Exchange with Mass Spectrometric Analysis (ssHDX-MS)

Moussa, Ehab M., Wilson, Nathan E., Zhou, Qi Tony, Singh, Satish K., Nema, Sandeep, Topp, Elizabeth M.

Journal:

Pharmaceutical Research

Année:

2018

Langue:

english

Fichier:

PDF, 2.10 MB

english, 2018

41

The inhibitory effects of eighteen front-line antibiotics on the substrate uptake mediated by human Organic anion/cation transporters, Organic anion transporting polypeptides and Oligopeptide transporters in in vitro models

Lu, Xiaoxi, Chan, Ting, Zhu, Ling, Bao, Xiaofeng, Velkov, Tony, Zhou, Qi Tony, Li, Jian, Chan, Hak-Kim, Zhou, Fanfan

Journal:

European Journal of Pharmaceutical Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 1.76 MB

english, 2018

42

Efficacy of systemically administered polymyxins in mouse burn wound infection caused by multidrug-resistant Gram-negative pathogens: A proof-of-concept study

Lin, Yu-Wei, Chen, Ke, Wang, Jiping, Velkov, Tony, Zhou, Qi, Li, Jian

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2018

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2018

43

Qualitative and quantitative characterization of composition heterogeneity on the surface of spray dried amorphous solid dispersion particles by an advanced surface analysis platform with high surface-sensitivity and superior spatial resolution

Bhujbal, Sonal V, Zemlyanov, Dmitry, Cavallaro, Alex-Anthony, mangal, sharad, Taylor, Lynne S., Zhou, Qi Tony

Journal:

Molecular Pharmaceutics

Année:

2018

Langue:

english

Fichier:

PDF, 870 KB

english, 2018

44

Entry Properties and Entry Inhibitors of a Human H7N9 Influenza Virus

Si, Youhui, Li, Jianguo, Niu, Yuqiang, Liu, Xiuying, Ren, Lili, Guo, Li, Cheng, Min, Zhou, Hongli, Wang, Jianwei, Jin, Qi, Yang, Wei, Wang, Tony

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 2.65 MB

english, 2014

45

Improved physical stability and aerosolization of inhalable amorphous ciprofloxacin powder formulations by incorporating synergistic colistin

Shetty, Nivedita, Ahn, Patricia, Park, Heejun, Bhujbal, Sonal, Zemlyanov, Dmitry, Cavallaro, Alex-Anthony, mangal, sharad, Li, Jian, Zhou, Qi Tony

Journal:

Molecular Pharmaceutics

Année:

2018

Langue:

english

Fichier:

PDF, 7.45 MB

english, 2018

46

Lipidomic Analysis of the Outer Membrane Vesicles from Paired Polymyxin-Susceptible and -Resistant Klebsiella pneumoniae Clinical Isolates

Jasim, Raad, Han, Mei-Ling, Zhu, Yan, Hu, Xiaohan, Hussein, Maytham, Lin, Yu-Wei, Zhou, Qi (Tony), Dong, Charlie, Li, Jian, Velkov, Tony

Journal:

International Journal of Molecular Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 3.92 MB

english, 2018

47

Intracellular localization of polymyxins in human alveolar epithelial cells

Ahmed, Maizbha U, Velkov, Tony, Zhou, Qi Tony, Fulcher, Alex J, Callaghan, Judy, Zhou, Fanfan, Chan, Kim, Azad, Mohammad A K, Li, Jian

Journal:

Journal of Antimicrobial Chemotherapy

Année:

2018

Langue:

english

Fichier:

PDF, 2.04 MB

english, 2018

48

Electric-Field-Assisted Facile Synthesis of Metal Nanoparticles

Zhou, Qi, Zhang, Jingjing, Saba, Tony, Yue, Zhen, Li, Wei, Anderson, James A., Wang, Xiaodong

Journal:

ACS Sustainable Chemistry & Engineering

Année:

2018

Langue:

english

Fichier:

PDF, 4.92 MB

english, 2018

49

Novel Polymyxin Combination with Antiretroviral Zidovudine Exerts Synergistic Killing against NDM-producing MDR Klebsiella pneumoniae

Lin, Yu-Wei, Abdul Rahim, Nusaibah, Zhao, Jinxin, Han, Mei-Ling, Yu, Heidi H., Wickremasinghe, Hasini, Chen, Ke, Wang, Jiping, Paterson, David L., Zhu, Yan, Rao, Gauri G., Zhou, Qi Tony, Forrest, Alan

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2019

Fichier:

PDF, 3.01 MB

2019

50

Formulation and Manufacturing of Solid Dosage Forms

Zhou, Qi Tony, Li, Tonglei

Journal:

Pharmaceutical Research

Année:

2019

Langue:

english

Fichier:

PDF, 947 KB

english, 2019